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Unit 1　Translation Skills 1

Text A　The Heritage of Pharmacy 1

Text B　Introduction of the Scientific Viewpoint 3

Additional Information 6

Exercises 9

Unit 2　Inorganic Chemistry 10

Text　Important Biomolecules (1) 10

Additional Information 13

Exercises 14

Unit 3　Organic Chemistry ＆ Biochemistry 15

Text A　Important Biomolecules (2) 15

Text B　Biochemical Reactions 17

Text C　Heterocycles 20

Reading Material Optimization of Reactions 26

Additional Information 30

Exercises 31

Unit 4 Analytical Chemistry 33

Text A Some General Notices and Requirements applying to tests and assays 33

Text B Acacia 40

Text C Alginic Acid 42

Text D Aspirin 43

Reading Material The United States Pharmacopeia and the National Formulary 45

Additional Information 49

Exercises 50

Unit 5 Microbiology 53

Text A The Microbial World 53

Text B Aseptic Technique 54

Text C The Diversity of Microorganisms 55

Reading Material Measuring Bacterial Growth 57

Additional Information 61

Exercises 62

Unit 6 Molecular Biology 65

Text A Creating the Clone 65

Text B Introduction of Foreign DNA Molecules into Bacteria 66

Text C Selection of cDNA Clones 67

Text D Southern Blotting 68

Text E Polymerase Chain Reaction 69

Reading Material A Genomic DNA Clones 69

Reading Material B Production of Mammalian Proteins in Bacteria 70

Additional Information 70

Exercises 71

Unit 7 Pharmacology and Pharmaceutics 73

Text A Introduction to Drugs 73

Text B Oral Route 77

Text C Dosage Forms and Routes of Administration 81

Additional Information 85

Exercises 88

Unit 8 Introduction to Inserts for Imported Drugs 90

Text A Diaformin Tablets 90

Text B Angised Tablets 91

Text C Ciprofloxacin 94

Additional Information 101

Exercises 105

Unit 9 Fermentation Processes 107

Text A Strain Improvement 107

Text B Fermentation 109

Text C Antibiotics 111

Text D Bioreactors 115

Reading Material Growth and Culturing of Bacteria 119

Additional Information 120

Exercises 121

Unit 10 Separation Processes 123

Text A Downstream Processing in Biotechnology 123

Text B Filtration 124

Text C Release of Intracellular Components 127

Text D Concentration of Biological Products 129

Reading Material Purification by Chromatography 133

Additional Information 134

Exercises 135

Unit 11 Dosage Forms Production 137

Text A Pharmaceutic Ingredients 137

Text B Tablets 141

Text C Hard Gelatin Capsules 147

Text D The Preparation of Parenteral Products 149

Text E Rectal Route,Epicutaneous Route,and Ocular,Oral,Nasal Routes 152

Additional Information 155

Exercises 156

Unit 12 GMP Guidance for Industry 158

Text A Laboratory Controls 158

Text B Aseptic Processes Design 162

Text C Air Filtration 164

Text D Injections—Methods of Sterilization 165

Additional Information 170

Exercises 171

Unit 13 Developments 172

Text A Pharmacognosy in the 21st Century 172

Text B Recent Developments in Combinatorial Organic Synthesis 177

Text C Fishing for Drugs from the sea:status and strategies 182

Additional Information 188

Exercises 188

Unit 14 Natural Products for Health-promoting 189

Text A Health-promoting Properties of Flavonoids 189

Text B Help for the Immune System 191

Text C Herbs with Anticancer Activity 192

Exercises 195

Unit 15 Bioinformatics 197

Text A What is Bioinformatics 197

Text B Database resources of the National Center for Biotechnology Information(NCBI) 197

Text C What Bioinformatics Can Do 198

Text D Alignment 198

Reading Material Protein Structure Prediction Method 200

Additional information 202

Exercises 203

Unit 16 Chemical Abstracts 204

Text A A Short Guide to Writing Abstracts 204

Text B Abstracts 207

Additional Information 211

Appendix Ⅰ Glossary of Prefixes,Roots,Suffixes 214

Appendix Ⅱ Glossary of Molecular Cell Biology 216

Appendix Ⅲ Vocabulary 232