图书介绍

生物统计学和生物信息学最新进展 英文pdf电子书版本下载

生物统计学和生物信息学最新进展  英文
  • 范剑青,林希虹,刘军主编 著
  • 出版社: 北京:高等教育出版社
  • ISBN:9787040247558
  • 出版时间:2008
  • 标注页数:280页
  • 文件大小:23MB
  • 文件页数:291页
  • 主题词:生物统计-文集-英文;生物信息论-文集-英文

PDF下载


点此进入-本书在线PDF格式电子书下载【推荐-云解压-方便快捷】直接下载PDF格式图书。移动端-PC端通用
种子下载[BT下载速度快] 温馨提示:(请使用BT下载软件FDM进行下载)软件下载地址页 直链下载[便捷但速度慢]   [在线试读本书]   [在线获取解压码]

下载说明

生物统计学和生物信息学最新进展 英文PDF格式电子书版下载

下载的文件为RAR压缩包。需要使用解压软件进行解压得到PDF格式图书。

建议使用BT下载工具Free Download Manager进行下载,简称FDM(免费,没有广告,支持多平台)。本站资源全部打包为BT种子。所以需要使用专业的BT下载软件进行下载。如 BitComet qBittorrent uTorrent等BT下载工具。迅雷目前由于本站不是热门资源。不推荐使用!后期资源热门了。安装了迅雷也可以迅雷进行下载!

(文件页数 要大于 标注页数,上中下等多册电子书除外)

注意:本站所有压缩包均有解压码: 点击下载压缩包解压工具

图书目录

Part Ⅰ Analysis of Survival and Longitudinal Data 3

Chapter 1 Non-and Semi-Parametric Modeling in Survival Analysis Jianqing Fan,Jiancheng Jiang 3

1 Introduction 3

2 Cox's type of models 4

3 Multivariate Cox's type of models 14

4 Model selection on Cox's models 24

5 Validating Cox's type of models 27

6 Transformation models 28

7 Concluding remarks 30

References 30

Chapter 2 Additive-Accelerated Rate Model for Recurrent Event Donglin Zeng,Jianwen Cai 35

1 Introduction 35

2 Inference procedure and asymptotic properties 37

3 Assessing additive and accelerated covariates 40

4 Simulation studies 41

5 Application 42

6 Remarks 43

Acknowledgements 44

Appendix 44

References 48

Chapter 3 An Overview on Quadratic Inference Function Approaches for Longitudinal Data John J.Dziak,Runze Li,Annie Qu 49

1 Introduction 49

2 The quadratic inference function approach 51

3 Penalized quadratic inference function 56

4 Some applications of QIF 60

5 Further research and concluding remarks 65

Acknowledgements 68

References 68

Chapter 4 Modeling and Analysis of Spatially Correlated Data Yi Li 73

1 Introduction 73

2 Basic concepts of spatial process 76

3 Spatial models for non-normal/discrete data 82

4 Spatial models for censored outcome data 88

5 Concluding remarks 96

References 96

Part Ⅱ Statistical Methods for Epidemiology 103

Chapter 5 Study Designs for Biomarker-Based Treatment Selection Amy Laird,Xiao-Hua Zhou 103

1 Introduction 103

2 Definition of study designs 104

3 Test of hypotheses and sample size calculation 108

4 Sample size calculation 111

5 Numerical comparisons of efficiency 116

6 Conclusions 118

Acknowledgements 121

Appendix 122

References 126

Chapter 6 Statistical Methods for Analyzing Two-Phase Studies Jinbo Chen 127

1 Introduction 127

2 Two-phase case-control or cross-sectional studies 130

3 Two-phase designs in cohort studies 136

4 Conclusions 149

References 151

Part Ⅲ Bioinformatics 159

Chapter 7 Protein Interaction Predictions from Diverse Sources Yin Liu,Inyoung Kim,Hongyu Zhao 159

1 Introduction 159

2 Data sources useful for protein interaction predictions 161

3 Domain-based methods 163

4 Classification methods 169

5 Complex detection methods 172

6 Conclusions 175

Acknowledgements 175

References 175

Chapter 8 Regulatory Motif Discovery:From Decoding to Meta-Analysis Qing Zhou,Mayetri Gupta 179

1 Introduction 179

2 A Bayesian approach to motif discovery 181

3 Discovery of regulatory modules 184

4 Motif discovery in multiple species 189

5 Motif learning on ChIP-chip data 195

6 Using nucleosome positioning information in motif discovery 201

7 Conclusion 204

References 205

Chapter 9 Analysis of Cancer Genome Alterations Using Single Nucleotide Polymorphism(SNP)Microarrays Cheng Li,Samir Amin 209

1 Background 209

2 Loss of heterozygosity analysis using SNP arrays 212

3 Copy number analysis using SNP arrays 216

4 High-level analysis using LOH and copy number data 224

5 Software for cancer alteration analysis using SNP arrays 229

6 Prospects 231

Acknowledgements 231

References 231

Chapter 10 Analysis of ChIP-chip Data on Genome Tiling Microarrays W.Evan Johnson,Jun S.Liu,X.Shirley Liu 239

1 Background molecular biology 239

2 A ChIP-chip experiment 241

3 Data description and analysis 244

4 Follow-up analysis 249

5 Conclusion 254

References 254

Subject Index 259

Author Index 261

精品推荐